Michael Short, who has been in charge for three-and-a-half years, will be replaced by deputy news editor Jane Lavender.
Crime reporter Julian Thorpe has been promoted to deputy news editor.
Editor-in-chief Ian Savage told How-Do:
I am delighted to announce these two well deserved promotions in our editorial department. I am sure that both Jane and Julian will work as hard as ever in their new roles and I wish them all the best.
The most recent ABC figures show circulation of the Bolton News was down 10.2 per cent in the second half of 2011 to 20,571