Liverpool Daily Post editor Jane Wolstenholme is leaving the paper after four years in the post to help run her husband's PR company and embark on a book writing career.
Her husband Jon Brown who was acting editor at the Post's sister title the Echo, left the Liveropool Post and Echo in the October 2005 as head of multimedia operation to set up the company.
Wolstenholme, 32, has also secured a book deal for two novels with Simon and Schuster.
She said: "I have had four very enjoyable, challenging and rewarding years as editor and feel very privileged to have worked with some of the most talented people in the regional press.
"I will be sad to leave but have no doubt that the title will go from strength to strength."
During her editorship Wolstenholme took the Post through a major relaunch and the paper was named North West Newspaper of the Year.
Before she leaves the paper in early Wolstenholme hopes to boost readership by sending out 6,000 copies of the paper to targeted businesses and to readers by street vendors while strengthening editorial and the commercial operation.
Part of the plan includes the launch of a new weekly supplement called Style City to celebrate the growth people living in Liverpool's city centre.
Wolstenholme said: "These changes will ensure the Liverpool Daily Post enters 2007 in the very best shape for my successor to build upon."
Managing director of Trinity Mirror North West & North Wales Sara Wilde said: "Jane has been a superb editor of the Liverpool Daily Post and we are very sad to see her go.
"However, we wish her all the very best and are delighted she is staying on to deliver the first stage of the exciting development plans we have for the paper."
Wolstenholme started out as a graduate trainee at the Liverpool Echo 10 years ago and has spent all her career with Trinity Mirror apart from a stint on the Daily Mail.